Developed in 2012, Leadership HSC is a program tailored for first-year HSC students, aiming to foster inter-college educational experiences. The program equips students with the essential tools to emerge as effective leaders within the OU Health Sciences campus community. Participants learn about themselves, their peers, and campus resources, gaining experience that broadens their knowledge and familiarity with the OU Health Sciences campus and community.

Each year, the Leadership HSC Class is comprised of a select group of 50 first-year students spanning all seven colleges at the OU Health Sciences campus. These students have distinguished themselves as leaders in their colleges and are in good academic standing. Students are selected based on their leadership ability, recognized strength to empower their peers, and passion for the OU Health Sciences community. Participation in the Leadership HSC Class is a prestigious honor, recognizing both the students and the colleges they represent.